CASE REPORT


Case of Cerulean Cataract 33-year-old man presented to the ophthalmology clinic with a gradual decrease in vision in both eyes for three years. The best-corrected visual acuity was 20/60 and 20/80 in the right and left eye, respectively.


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Cerulean Cataract

The intraocular pressure was 14 mm Hg in both eyes. Slit-lamp examination of both eyes releveled multiple bluecolored opacities spread throughout the cortex of the lens with opacified central suture of blueish hue more prominent in the left eye.

Posterior segment examination was unremarkable in both eyes. On the basis of appearance, bilateral nature, his cataracts were diagnosed as most likely a variant of cerulean cataracts with a stellate component.

DISEASE of Cerulean Cataract


Cerulean cataracts, also known as blue dot cataracts, are developmental cataracts characterized by blue and white opacifications scattered in the nucleus and cortex of the lens.

Cerulean Cataract

Patients with cerulean cataracts are usually asymptomatic until 18-24 months of age and often do not need them removed before adulthood.

MANAGEMENT of Cerulean Cataract


Serial evaluations and surgery

There are no known treatments to prevent the formation and progression of cerulean cataracts. Serial eye evaluations and eventual cataract surgery are the standards of care.

HOW TO TAKE Slit lamp EXAM IMAGES BY A SMARTPHONE?

Smartphone slit-lamp photography is the new advancement in the field of science and technology in which the photographs of the desired slit-lamp finding can be taken with smartphones by using the slit-lamp adaptors.

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Read more about another types of cataracts: Morgagnian Cataract,Rosette-Shaped Cataract,Christmas tree cataract and Coats disease.

REFERENCES


1. Xiao X, Li W, Wang P, et al. Cerulean cataract mapped to 12q13 and associated with a novel initiation codon mutation in MIP. Mol Vis. 2011;17:2049-2055.

2. Litt M, Carrero-Valenzuela R, LaMorticella DM, et al. Autosomal Dominant Cerulean Cataract Is Associated with a Chain Termination Mutation in the Human β-Crystallin Gene CRYBB2. Human Molecular Genetics. 1997;6(5):665-668. doi:10.1093/hmg/6.5.665

3. Nandrot E, Slingsby C, Basak A, et al. Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts. Journal of Medical Genetics. 2003;40(4):262-267. doi:10.1136/jmg.40.4.262

4. Vanita V, Singh D, Robinson PN, Sperling K, Singh JR. A novel mutation in the DNA-binding domain of MAF at 16q23.1 associated with autosomal dominant “cerulean cataract” in an Indian family. American Journal of Medical Genetics Part A. 2006;140A(6):558-566. doi:10.1002/ajmg.a.31126

5. Ram J, Singh A. Cerulean cataract. QJM: An International Journal of Medicine. 2019;112(9):699-699. doi:10.1093/qjmed/hcz038

smartphone slit-lamp photography

RETINAL IMAGING BY YOUR SMARTPHONE

RETINAL IMAGING BY YOUR SMARTPHONE

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