LASIK, laser-assisted in situ keratomileusis, reshapes the corneal stroma with an excimer laser beneath a hinged corneal flap to correct myopia, hyperopia, and astigmatism.

It remains the most widely performed refractive procedure worldwide, and its long track record is both its main selling point and the source of most of what is now known about its limitations.

Patient selection, more than any technical refinement of the laser itself, is what separates a satisfied LASIK patient from a complicated one.


How LASIK Works

A femtosecond laser or mechanical microkeratome creates a thin, hinged flap in the anterior corneal stroma. This flap is lifted, exposing the underlying stromal bed.

An excimer laser then ablates stromal tissue in a pattern calculated from the patient’s refractive error, reshaping the corneal curvature to correct focusing power. For myopia, tissue is removed centrally to flatten the cornea; for hyperopia, tissue is removed in the periphery to steepen it.

The flap is then repositioned without sutures, relying on the natural adhesion of the corneal epithelium and stroma to hold it in place while it heals.


Patient Selection

Candidacy depends on a combination of refractive stability, corneal thickness, and a normal, regular corneal topography.

  • Stable refraction for at least a year, since LASIK performed on a still-changing prescription risks under- or over-correction as the eye continues to change
  • Adequate corneal thickness to allow flap creation and stromal ablation while preserving a sufficient residual stromal bed, generally at least 250 microns, to avoid destabilising the cornea
  • Normal corneal topography, with no evidence of keratoconus or forme fruste keratoconus, which is an absolute contraindication given the risk of inducing ectasia
  • Realistic expectations, particularly around night vision symptoms and the likelihood of still needing reading glasses with age regardless of the refractive outcome achieved

Topographic screening for subclinical keratoconus is arguably the single most important step in the entire preoperative workup, since operating on an unrecognised ectatic cornea is the pathway to the procedure’s most feared complication.


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The Procedure

LASIK refractive surgery: a close-up view of a patient undergoing laser-assisted in situ keratomileusis, with a lid speculum in place and the eye positioned under the excimer laser

The procedure is performed under topical anaesthesia with the patient awake, typically taking only a few minutes per eye. A lid speculum keeps the eye open, and the patient is asked to fixate on a target light while the laser tracks eye movement in real time to keep the ablation centred.

Most patients notice improved vision within hours, with further stabilisation over the following days to weeks as the flap heals and any residual corneal oedema resolves.


Outcomes

Large outcome studies consistently show that the large majority of patients achieve uncorrected vision of 20/20 or better, and the great majority achieve at least 20/40, sufficient for driving without correction in most jurisdictions.

Patient satisfaction rates are generally high, though a meaningful minority of patients report persistent dry eye or night vision disturbances, such as glare and haloes, that affect their day-to-day experience even when their measured visual acuity is excellent.

This gap between objective visual acuity outcomes and subjective patient-reported symptoms is worth discussing explicitly during counselling, since a technically successful result on the chart does not guarantee an entirely symptom-free patient.


Complications

  • Dry eye, the most common postoperative complaint, related to corneal nerve transection during flap creation; usually improves over months but can be persistent in a minority of patients
  • Flap complications, including striae, displacement, or epithelial ingrowth beneath the flap, more common with mechanical microkeratome flaps than with femtosecond-created flaps
  • Under- or over-correction, sometimes requiring a secondary enhancement procedure once the refraction has stabilised
  • Night vision disturbances, including glare and haloes, more likely in patients with larger pupils relative to the treatment zone
  • Post-LASIK ectasia, progressive corneal steepening in a cornea that was not adequately screened preoperatively, the most serious long-term complication and largely avoidable with proper topographic screening
  • Infectious or inflammatory keratitis, uncommon but requiring prompt recognition and treatment when it occurs

Ectasia is the complication that shapes preoperative screening protocols more than any other, precisely because it is rare but largely preventable through careful patient selection rather than treatable once established.


Alternatives to LASIK

Photorefractive keratectomy (PRK) achieves similar refractive outcomes without creating a corneal flap, removing the epithelium directly before laser ablation. It avoids flap-related complications entirely but involves a longer, more uncomfortable recovery in the days after surgery.

PRK is often preferred in patients with thinner corneas or certain occupational or lifestyle risks of eye trauma, where flap-related risk is a greater concern.

Small incision lenticule extraction (SMILE) is a newer alternative that removes a lenticule of stromal tissue through a small incision without a full flap, offering a different risk profile that is still being compared against LASIK in longer-term studies.


Prognosis

LASIK has a strong long-term safety record when performed on properly screened candidates, with refractive stability generally maintained over many years.

Patients should be counselled that presbyopia will still develop with age regardless of the refractive correction achieved, since LASIK corrects distance focusing power but does not prevent the natural loss of accommodation that comes with an ageing lens.

Overall, patient-reported satisfaction remains high in most long-term follow-up studies, though the small subset of patients with persistent dry eye or visual disturbance symptoms is a genuine and predictable minority worth setting expectations for before surgery, not after.


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References

  1. Sandoval HP, Donnenfeld ED, Kohnen T, et al. Modern laser in situ keratomileusis outcomes. Journal of Cataract and Refractive Surgery. 2016.
  2. Solomon KD, Fernandez de Castro LE, Sandoval HP, et al. LASIK world literature review: quality of life and patient satisfaction. Ophthalmology. 2009.
  3. Randleman JB, Woodward M, Lynn MJ, Stulting RD. Risk assessment for ectasia after corneal refractive surgery. Ophthalmology. 2008.
  4. LASIK. EyeWiki, American Academy of Ophthalmology.
  5. LASIK. StatPearls, NCBI Bookshelf.